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infusion has been usedfor prophylaxis of stress ulcers. The reaction is catalyzed by car-bonic anhydrase, which leads to the pro-duction of H+ ions in the cytoplasm, whichare then transported acrossthe membraneto the lumen ofthe intracellularcanaliculusby a H+/K+-ATPase proton pump. Litwin MS, Lubeck DP, Henning JM, Carroll PR (?998).
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